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Besivance (Besifloxacin)



Active ingredient: Besifloxacin

Dosages: 5ml

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What is Besivance (Besifloxacin)?

Besivance (Besifloxacin) is a powerful antibiotic eye drop specifically designed to treat bacterial conjunctivitis, commonly known as pink eye. As part of the fluoroquinolone class of antibiotics, Besifloxacin offers broad-spectrum antibacterial activity, effectively targeting a wide array of bacteria responsible for eye infections. It is particularly effective against strains that have developed resistance to other antibiotics, making it an essential option in cases where typical treatments fail. The drops are applied directly to the eye three times daily, ensuring concentrated treatment directly at the site of infection.

Besivance is known for its precise formulation, which has been specifically developed to provide robust antibacterial effects while being suitable for direct ocular application. This tailored approach ensures that the treatment is both effective and efficient, directly addressing the pathogens involved in the infection without unnecessary systemic exposure. As such, this antibiotic remains a preferred choice among healthcare providers for its targeted action and reliability in treating resistant cases of bacterial conjunctivitis.

Frequently Asked Questions about Besivance (Besifloxacin)

What is Besivance (Besifloxacin) Ophthalmic Suspension 0.6 used for?

Besivance Besifloxacin Ophthalmic Suspension 0.6% is primarily used to treat bacterial conjunctivitis, also known as pink eye. This antibiotic eye drop targets a wide array of bacteria, including strains resistant to other treatments. By inhibiting the bacteria’s ability to replicate DNA, this drug effectively clears infections, leading to reduced inflammation, redness, and discomfort in the eye. It’s a targeted approach that makes this antibiotic a strong option for those needing quick and effective relief from bacterial eye infections.

How to use Besivance eye drops?

Using Besivance eye drops correctly is crucial for the treatment’s success:

  • Wash your hands thoroughly.
  • Shake the bottle gently before use.
  • Tilt your head back and pull down your lower eyelid to create a small pocket.
  • Hold the dropper above the eye and squeeze one drop into the pocket without letting the dropper touch your eye.
  • Close your eyes for 2-3 minutes, tip your head down as though looking at the floor.
  • Try not to blink or rub your eye.
  • Repeat these steps for your other eye if prescribed.

How often is Besivance taken?

Besivance is typically prescribed to be used three times a day, with doses spaced about 8 hours apart. This frequency can effectively maintain adequate levels of medication in the eye to combat bacterial infections effectively. The duration of treatment usually lasts for 7 days, but always follow the specific instructions given by your healthcare provider.

Besivance vs. Ciprofloxacin: How do they compare?

While both Besivance and Ciprofloxacin are used to treat eye infections, Besivance is specifically formulated to combat bacteria that are resistant to typical antibiotics like Ciprofloxacin. Besivance contains Besifloxacin, a newer generation fluoroquinolone, offering broader antibacterial coverage and a different resistance profile compared to Ciprofloxacin, making it a superior choice for certain types of bacterial conjunctivitis. This broader spectrum of activity means that Besifloxacin can effectively treat a wider range of bacterial pathogens, including those that do not respond well to older fluoroquinolones like Ciprofloxacin. Additionally, Besifloxacin is designed to adhere well to cells on the surface of the eye, increasing its contact time and enhancing its effectiveness at lower concentrations. These properties help Besivance provide more potent and efficient treatment for patients suffering from severe and drug-resistant eye infections, thereby ensuring better outcomes in managing bacterial eye conditions.

What does Besivance do?

Besivance acts as a potent antibacterial agent that works by inhibiting essential enzymes necessary for bacterial DNA replication. This action stops bacteria from reproducing, thereby halting the spread of the infection. The drug quickly reduces symptoms of bacterial conjunctivitis, such as redness, itchiness, and discharge, promoting faster healing and comfort. Specifically, it targets the DNA gyrase and topoisomerase IV enzymes, which are crucial for bacterial DNA processes. By blocking these enzymes, Besifloxacin prevents the bacteria from replicating and repairing their DNA, effectively killing them and clearing up the infection. This targeted approach not only alleviates the uncomfortable symptoms but also addresses the underlying cause of the infection, making it an effective solution for bacterial eye infections that require prompt and decisive treatment.

Besivance for pink eye: Is it effective?

Besivance is highly effective for treating bacterial forms of pink eye, particularly those caused by strains resistant to other antibiotics. Its specialized formulation allows it to quickly reduce key symptoms like redness, puffiness, and eye discharge, effectively clearing the infection with a full course of treatment. Besivance works by directly targeting the pathogens responsible for the infection, providing rapid relief from the discomfort and visual disturbance that bacterial conjunctivitis can cause. The medication’s ability to adhere to the ocular surface enhances its effectiveness, ensuring that the active ingredient remains in contact with the eye for a sufficient duration to combat the bacteria effectively.

The efficacy of Besivance in treating pink eye is notable especially in cases where the bacteria have developed resistance to commonly used antibiotics, making it a critical option in the arsenal against eye infections. By disrupting the bacterial DNA replication process, Besifloxacin not only stops the growth of the bacteria but also prevents them from spreading further, which accelerates the healing process. For patients suffering from the acute symptoms of bacterial conjunctivitis, the antibiotic provides a reliable solution that can lead to improvement within a few days, restoring eye health and comfort rapidly.

Besivance coupon: Where can I find one?

Coupons for Besivance can often be found through the manufacturer’s website or through various coupon and savings programs online. These discounts can help make the treatment more affordable. Additionally, checking with your healthcare provider or pharmacist for potential savings offers or rebate programs is also recommended.

What are some alternatives to Besivance?

If Besivance is not suitable or available, several other antibiotic eye drops can be used as alternatives, each offering effective treatment for bacterial conjunctivitis. Some of these alternatives include:

  • Vigamox (Moxifloxacin): A broad-spectrum antibiotic that is particularly effective against a wide range of bacteria, making it a popular choice for treating bacterial eye infections.
  • Polytrim (Polymyxin B/Trimethoprim): This combination is effective against a variety of bacteria and is often used for mild to moderate infections.
  • Tobramycin: An aminoglycoside antibiotic used for its robust activity against gram-negative organisms.

While these alternatives can be effective, their efficacy against resistant strains may vary compared to Besifloxacin, which is known for its effectiveness against bacteria that have developed resistance to other treatments.

How long to use Besivance?

The typical duration for using Besivance eye drops is about 7 days, depending on the severity of the infection and the specific recommendations of your healthcare provider. It’s crucial to complete the full course of therapy to ensure the infection is fully eradicated and to prevent resistance. In some cases, based on the progress of healing or the persistence of symptoms, your healthcare provider might adjust the duration of treatment. Stopping the medication prematurely can lead to a resurgence of the infection and increase the risk of developing antibiotic resistance. Therefore, even if symptoms appear to improve or completely resolve before the end of the prescribed treatment period, it is important to continue using the antibiotic for the full duration as directed to ensure a thorough recovery.

Does Besivance expire?

Yes, like all medications, besifloxacin eye drops have an expiration date, which is found on the bottle label. It’s important not to use the eye drops beyond this date as the effectiveness can diminish over time, and using expired medication can be unsafe. Always ensure you check the expiry date before application and dispose of any expired or unused medication appropriately.

How long does Besivance last after opening?

Once opened, Besivance should be used as prescribed, typically within a set number of days. It’s important not to use the eye drops beyond this period as the sterility of the solution could be compromised. Always refer to the packaging or consult your pharmacist for the exact duration the drops remain usable after opening. Generally, opened bottles of Besifloxacin eye drops are recommended to be discarded 28 days after opening, to ensure that the medication remains effective and safe to use. This precaution helps prevent the risk of eye infections due to contaminated drops.

Where can I find more information about this drug?

For more detailed information about Besivance (Besifloxacin), you can visit here. Additionally, consulting your pharmacist or healthcare provider will provide comprehensive details and personalized advice tailored to your needs.

Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Always seek the guidance of a qualified healthcare professional before making any changes to your health care, including medications. This content does not substitute for professional medical diagnosis, advice, or treatment. If you have any specific concerns or questions about a medical condition, consult your doctor or another qualified health provider promptly. Never disregard professional medical advice or delay seeking it because of something you have read in this document.

By Dr. Emma Lawson
Medically Reviewed by Dr. Nicholas Argento
Last Updated: July 1, 2024